4-苄基-2-甲基-1,2,4-噻二唑-3,5-二酮
2019-04-01
产品详情
- 产地 加拿大
- Cas:327036-89-5
- 价格:99
- 产品名称4-苄基-2-甲基-1,2,4-噻二唑-3,5-二酮
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- 简介
货号:02-285725
中文名称:4-苄基-2-甲基-1,2,4-噻二唑-3,5-二酮
英文名称:rac N-Benzyl Nebivolol
CAS号:327036-89-5
重量:10mg
重量:100mg
分子式:C10H10N2O2S
别名:GSK-3? Inhibitor I, TDZD-8
应用介绍:Glycogen Synthase Kinase-3? is a highly conserved ubiquitously expressed serine/threonine protein kinase involved in signal transduction cascades of multiple cellular processes. TDZD-8 is a thiadiazolidinone (TDZD) analogue that acts as a highly selective, non-ATP competitive inhibitor of GSK-3? ( IC50 =2nM). Binds to the active site of GSK-3?. Does not significantly affect the activities of Cdk-1/cyclin B, CK-II, PKA, and PKC (IC50 >100nM).
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