产品展厅
AST-1306
2019-04-01
产品详情
- 产地 加拿大
- Cas:897383-62-9
- 价格:99
- 产品名称AST-1306
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- 简介
货号:01-790045
中文名称:AST-1306
英文名称:Atazanavir Bisulfate Salt
See A790051
CAS号:897383-62-9
重量:5mg
重量:50mg
分子式:C24H18ClFN4O2
别名:N-[4-[[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]amino]quinazolin-6-yl]acrylamide; N-[4-[[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-propenamide; ALS1306; AST 1306; AST 6;
应用介绍:AST-1306 is a selective irreversible inhibitor of the epidermal growth factor receptor (EGFR) 1 and 2. Studies show that AST-1306 inhibited the enzymatic activities of wild-type EGF) and ErbB2 as well as EGFR resistant mutant in both cell-free and cell-based systems. AST-1306 was more effective in inhibiting tumors with ErbB2-overexpressing cells than EGFR-overexpressing tumor.
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