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磷灰石-D8盐酸盐
2019-04-01
产品详情
- 产地 加拿大
- 价格：99
- 产品名称磷灰石-D8盐酸盐
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- 简介
货号：01-726152
中文名称：磷灰石-D8盐酸盐
英文名称：Apatinib 25-N-Oxide Dihydrochloride
CAS号：
重量：1mg
重量：10mg
分子式：C24H16D8ClN5O
别名：N-[4-(1-Cyanocyclopentyl-d8)phenyl]-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide; YN968D1-d8 Hydrochloride;
应用介绍：Labelled Apatinib (A726150). Apatinib is an orally available, small molecule multitargeted tyrosine kinase inhibitor. Apatinib selectively inhibits the vascular endothelial growth factor receptor-2 (VEGFR2). Apatinib functions by inhibiting VEGF-mediated endothelial cell migration and proliferation thus blocking new blood vessel formation in tumor tissue. Recent studies have shown that Apatinib enhances the efficacy of conventional chemotherapeutical drugs in side population (SP) cells and ABCB1-overexpressing leukemia cells.
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