产品展厅
芦荟素A RP107
2019-04-01
产品详情
- 产地 加拿大
- Cas：496864-16-5
- 价格：99
- 产品名称芦荟素A RP107
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- 简介
货号：01-575450
中文名称：芦荟素A RP107
英文名称：Aloisine RP106
CAS号：496864-16-5
重量：10mg
重量：100mg
分子式：C16H17N3O
别名：RP107, 7-n-Butyl-6-(4-hydroxyphenyl)-[5H]pyrrolo[2,3-b]pyrazine; 4-(7-Butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)phenol;
应用介绍：A cell-permeable pyrrolo-pyrazine compound that acts as a potent, selective, reversible, and ATP-competitive inhibitor of cyclin dependent kinases (Cdks: IC50 =150nM, 120 nM, 400 nM and 200 nM for Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, and Cdk5/p25, respectively). Also inhibits the activity of clycogen synthase kinase-3 (GSK-3,:(IC50 =500 nM and 1.5 uM for GSK-3a, GSK-3?, respectively), and c-Jun N-terminal kinase (JNK: IC50 approx. 3-10uM).
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