产品展厅
AG-490
2019-04-01
产品详情
- 产地 加拿大
- Cas：134036-52-5
- 价格：99
- 产品名称AG-490
查看相似产品 >
- 简介
货号：01-425000
中文名称：AG-490
英文名称：AG-1295
CAS号：134036-52-5
重量：25mg
重量：250mg
分子式：C17H14N2O3
别名：2-Cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-2-propenamide; Tyrphostin B 42;
应用介绍：A potent and specific inhibitor of the Jak-2 tyrosine kinase. In acute lymphoblastic leukemia (ALL) cells which abundantly express JAK-2, AG-490 dose-dependently inhibited DNA synthesis, blocked cell growth and induced apoptosis. AG-490 does not significantly inhibit other kinases such as Lck, Lyn, Btk, Syk and Src. AG-490 is cell permeable and is active in vivo.
...
联系我们
推荐产品
